Fluktuacije ulova nekih pelagičnih vrsta riba u Mediteranu

U radu su analizirani 63 godine dugački podaci o ulovu tune (Thunnus thynnus) i srdele (Sardina pilchardus) u Mediteranu, metodom spektralne (Fourierove) analize i kros korelacjom. Analiza je pokazala da ulov tune sadrži ciklične komponente od 2.6, 3.65, 5.64, 7.75, 10.34 and 15.5 i verovatno 31 godinu, dok su u ulovu srdele najizraženije bile amplitude od 2.44, 3.65, 6.2, 7.75 i 10.34 godina. Prema tome, oba su vremenska niza bila koherentna u ciklusima od 3.65, 7.75 i 10.34 godina. Takođe je ustanovljeno da je ulov tune koherentan sa indeksom severoatlantske oscilacije (NAO) i to u periodima od 2, 3.35, 4.43, 6.89, 10.34 i verovtno 31 godina. Ovo ukazuje da klimatski ciklusi utiču na fluktuacije populacije ove ribe. Nadalje, upoređenje fluktuacija ulova tune u zapadnom i istočnom Mediteranu je pokazalo da su one potpuno sinhrone

The Magnetic Electron Ion Spectrometer (MagEIS) Instruments Aboard the Radiation Belt Storm Probes (RBSP) Spacecraft

This paper describes the Magnetic Electron Ion Spectrometer (MagEIS) instruments aboard the RBSP spacecraft from an instrumentation and engineering point of view. There are four magnetic spectrometers aboard each of the two spacecraft, one low-energy unit (20–240 keV), two medium-energy units (80–1200 keV), and a high-energy unit (800–4800 keV). The high unit also contains a proton telescope (55 keV–20 MeV). The magnetic spectrometers focus electrons within a selected energy pass band upon a focal plane of several silicon detectors where pulse-height analysis is used to determine if the energy of the incident electron is appropriate for the electron momentum selected by the magnet. Thus each event is a two-parameter analysis, an approach leading to a greatly reduced background. The physics of these instruments are described in detail followed by the engineering implementation. The data outputs are described, and examples of the calibration results and early flight data presented

Deoxycholic Acid as a Modifier of the Permeation of Gliclazide through the Blood Brain Barrier of a Rat

Major problem for diabetic patients represents damage of blood vessels and the oxidative stress of the brain cells due to increased concentration of free radicals and poor nutrition of brain cells. Gliclazide has antioxidative properties and poor blood brain barrier (BBB) penetration. Bile acids are known for their hypoglycemic effect and as promoters of drug penetration across biological membranes. Accordingly, the aim of this study is to investigate whether the bile acid (deoxycholic acid) can change the permeation of gliclazide, through the blood brain barrier of a rat model type-1 diabetes. Twenty-four male Wistar rats were randomly allocated to four groups, of which, two were given alloxan intraperitoneally (100 mg/kg) to induce diabetes. One diabetic group and one healthy group were given a bolus gliclazide intra-arterially (20 mg/kg), while the other two groups apart from gliclazide got deoxycholic acid (4 mg/kg) subcutaneously. Blood samples were collected 30, 60, 150, and 240 seconds after dose, brain tissues were immediately excised and blood glucose and gliclazide concentrations were measured. Penetration of gliclazide in groups without deoxycholic acid pretreatment was increased in diabetic animals compared to healthy animals. Also in both, the healthy and diabetic animals, deoxycholic acid increased the permeation of gliclazide through that in BBB

Privredni ribolov na Dunavu u Srbiji

U radu se daje pregled slatkovodnog ribarstva sa aspekta upravljanja, ekspolatacije ribljih resursa, tržišta ribom, legislative koja uređuje delatnost ribarstva, kao i problemi sektora ribarstva u Srbiji. Istraživanje i analiza privrednog ribolova na Dunavu kroz Srbiju (588 km toka) sprovedeno je prikupljanjem podataka ribarske statistike za period od 1948. do 2010. godine, njihovim unošenjem u elektronsku bazu i analiziranjem uz korišćenje različitih metoda. Statistički podaci uključuju ukupan ulov, ulov rekreativnog i privrednog ribolova, ulov privredno značajnih vrsta i alohtonih vrsta. Korišćenjem anketnog upitnika za ribare dobijeni su podaci o demografskoj strukturi ribara koji se bave ribarenjem kao osnovnom delatnošću, o sastavu ulova, koliko je ribarstvo perspektivna privredna grana i koji su problemi i potencijalna rešenja. Većina ribara pripada starosnoj grupi koja je u opsegu od 45 do 50 godina. Privredni ribolov je važna ekonomska delatnost i predstavlja osnovni izvor prihoda za većinu ribara. Tržište slatkovodnom ribom je neuređena oblast koja zavisi od ličnog zalaganja i odgovornosti pojedinca koji ima interes u prodaji ribe. Ribarstvo na Dunavu u Srbiji je već dugi niz godina u procesu tranzicije ka tržišnoj ekonomiji. Dugoročne fluktuacije hidroloških podataka (vodostaj) upoređivane su sa fluktuacijama godišnjeg ulova ribe iz Dunava kako bi se uočila eventualna međusobna zavisnost i uporedili njihovi trendovi. Rezultati ovog istraživanja treba da posluže kao pregled stanja sektora sa svim postojećim nedostacima koje treba ispraviti u cilju što uspešnijeg upravljanja ribarstvom na Dunavu i ostalim rekama u Srbiji gde je zastupljen privredni ribolov

Treatment initiation for parkinson's disease in Australia 2013-2018 : a nation-wide study

Background Guidelines highlight the importance of an individualized approach to treatment initiation for Parkinson's disease. Our aim was to investigate initiation of anti-Parkinson medication in Australia from 2013-2018, and to determine factors predicting choice of initial treatment. Methods Cohort of new-users (N = 4,887) of anti-Parkinson medication aged >= 40 years were identified from a 10% random representative sample of national medication dispensing data from July-2013 to June-2018. Changes in treatment initiation were examined across the whole cohort and stratified by age and sex. Results Treatment initiation was most frequent with levodopa followed by non-ergot dopamine agonists (DAs) and anticholinergics. Two thirds initiated with levodopa across the study period. Initiation with non-ergot DAs increased from 22 to 27% (rate ratio, RR 1.23, 95% confidence interval, CI 1.02-1.47) and initiation with anticholinergics decreased from 6.9% to 2.4% (RR 0.34, 95% CI 0.21-0.55) from 2013-2018. Among persons aged >= 65 years, one third of women and one fourth of men initiated on levodopa. Among women aged = 65 years, consistent with current guidelines. Whilst the value of levodopa sparing strategies is unclear, treatment initiation with DA has become increasingly common relative to levodopa among women but not among men aged < 65 years.Peer reviewe

High Risk First Degree Relatives of Type 1 Diabetics: An Association with Increases in CXCR3 +

We analyzed the level of (a) CXCR3+ (Th1) and CCR4+ (Th2) T memory cells (b) interferon-γ inducible chemokine (IP-10)(Th1) and thymus and activation-regulated chemokine (TARC)(Th2), in 51 first degree relatives (FDRs) of type 1 diabetics (T1D) (17 high risk FDRs (GADA+, IA-2+) and 34 low risk FDRs (GADA−, IA-2−)), 24 recent-onset T1D (R-T1D), and 18 healthy subjects. T memory subsets were analyzed by using four-color immunofluorescence staining and flowcytometry. IP-10 and TARC were determined by ELISA. High risk FDRs showed higher levels of CXCR3+ and lower level of CCR4+ T memory cells compared to low risk FDRs (64.98 ± 5.19 versus 42.13 ± 11.11; 29.46 ± 2.83 versus 41.90 ± 8.58%, resp., P<0.001). Simultaneously, both IP-10 and TARC levels were increased in high risk versus low risk FDRs (160.12 ± 73.40 versus 105.39 ± 71.30; 438.83 ± 120.62 versus 312.04 ± 151.14 pg/mL, P<0.05). Binary logistic regression analysis identified the level of CXCR3+ T memory cells as predictors for high risk FDRs, together with high levels of IP-10. The results imply that, in FDRs, the risk for T1D might be strongly influenced by enhanced activity of Th1 and diminished activity of Th2 autoimmune response

Kvalitet mleka i osobine surutke dobijene pri proizvodnji Sjeničkog sira u industrijskim uslovima

Sjenica cheese is one of our best kinds of cheese from the group of white cheese in brine. Since the quality and overall value of the cheese depend on the quality and chemical composition of milk, before making cheese it is necessary to determine these parameters. Milk fat content in cow milk was 3.1%, protein 31.3%, dry matter 10.96%, casein 2.85%. Sheep milk of richer chemical composition had a dry matter 8.14%, fat 6.80%, protein 5.97%, casein 20.5%. Chemical composition of whey gauge the validity of keeping the process of making cheese. On the basis of dry matter content (cow whey 5.65% and sheep whey 7.5%), fat (cow whey 0.023%, sheep whey 0.62%), protein (cow whey 0.81% , sheep whey 1.44%), it is seen that the process of producing cheese is well managed with optimal utilization of milk ingredients.Sjenički sir je jedan od naših najboljih sireva iz grupe belih sireva u salamuri. Proizvodi se na individualnim gazdinstvima područja Sjeničko-pešterske visoravni. Sir se proizvodi od svežeg punomasnog kravljeg i očijeg mleka bez termičkog tretmana. Pošto kvalitet i opšte vrednosti sira zavise od kvaliteta i hemijskog sastava mleka , pre izrade sireva neophodno je odrediti te parametre. Sadržaj mlečne masti kod kravljeg mleka bio je 3.1%, proteina 3.31%, suve materije 10.96%, kazeina 2.85%. Ovčije mleko koje je bogatijeg hemijskog sastava imalo je suve materije 18.14%, masti 6.80%, proteina 5.97%, kazeina 5.20%. Na osnovu sadržaja suve materije (5.65% kravlja i 7.05% ovčja ) , masti ( 0.23% kravlja; 0.62% ovčija), proteina ( 0.81% kravlja, 1.44% ovčja), kod surutke vidi se da je proces proizvodnje sireva dobro vođen uz optimalnu iskorišćenost sastojaka mleka

A comparison of introductory programming courses between Portugal and Serbia

The goal of the study was to learn more about differences in academic performance, teaching, and assessment between introductory programming courses in Portugal and Serbia. Data about a selection of higher education courses were compiled and a comparison of student performance and methods employed in the classroom was performed. The obtained results are expected to serve as a basis for subsequent research on how to improve the current teaching practice in the two countries.info:eu-repo/semantics/publishedVersio